Rubina studied at Shimla Public School and completed her higher study from St. Bede's College, Shimla. She won the title of Miss Shimla in 2006. Then, she won the title of 2008's Miss North India Pageant in Chandigarh.
Rubina started her career in television with the serial "Chotti Bahu - Sindoor Bin Suhagan" which was aired on Zee TV from 2008 to 2010. After which she acted in the TV Series "Choti Bahu - Sawar Ke Rang Rachi" from 2011 to 2012 on Zee TV. She became really popular playing the character of Radhika in these TV Series.
Later on, the small screen actress worked in Saas Bina Sasural (2012) on Sony TV, Punar Vivah-Ek Nayi Umeed (2013) on Zee TV, Devon Ke Dev…Mahadev (2013) on Life OK, followed by many other popular TV Serials.
Rubina Dilaik also participated in Nachle Ve with Saroj Khan (2012) and in Box Cricket League 1 (2014-15) as a contestant. Many of her awards also include the award for Best Actress by Dada Saheb Phalke Film Foundation Awards in the Television Category in the year 2015. For her role as Radhika in Zee TV, she won many Zee Rishtey Awards in 2010 and 2011.
In addition, the star was listed in the Top 50 Sexiest Asian Women List by Eastern Eye where she grabbed the 26th rank. The actress is currently working as a female lead in Shakti-Astitva Ke Ehsaas Ki on Colors TV. For this role, she won the Best Actress Jury award of ITA awards in the year 2016.
In 2020-2021, she participated in Bigg Boss Season-14 as a contestant and become th winner. In 2021, she see in various music videos like Marjaneya (Neha Kakar), Galat (Asees Kaur), Tumse Pyaar Hai (Vishal Mishra). In 2022, she will seen in her Bollywood debut film "Ardh".